Standard Biological Indicators (BIs) are easy to use and are available for industrial or healthcare use. However, some manufacturing situations require a modified or specialty Biological Indicator to assist in validating the sterilization process. Manufacturers and validation specialists require unique tools where spore strips and ampoules are not suitable because of size, packaging or carrier material. Also, different materials may be compatible only with specific modes of sterilization.
Discs have advantages over spore strips due to their size. Several types and sizes of discs are available including: paper, borosilicate paper, and stainless steel. Steel discs are representative of materials found in an isolator, and are compatible with vapor hydrogen peroxide.
Woven cotton threads have been used at the interface of a syringe and plunger to show sterilant penetration and efficacy at that point. Other uses include placement in tubing and in small vials.
Braided steel wires can be placed into very small lumens and are easy to retrieve due their rigid nature.
To learn more about biological indicators that address the unique requirements of the medical device and pharmaceutical industries, contact Mesa Labs.