Immersion in a Chemical Solution

Liquid-Phase Sterilization

USP <1229.6> covers Liquid-Phase Sterilization. The traditional methods for sterilization include steam and dry heat, whereas Liquid-Phase sterilization requires immersion in a chemical solution. Per USP, “a number of chemical agents, such as aldehydes, acids, bases, and strong oxidants in solution, under the appropriate conditions, are capable of destroying bacteria and fungi, including both vegetative…